Chronic renal failure 50-100 IU/kg IV/SC 3 times/wk. Maintenance: Decrease dose by 25 IU/kg/dose.
Adult predialysis patient 50 IU/kg IV/SC 3 times/wk. Maintenance: 17-33 IU/kg 3 times/wk.
Acute hemodialysis patient 50 IU/kg IV/SC 3 times/wk. Maintenance: 30 & 100 IU/kg 3 times/wk.
Adult peritoneal dialysis patient 50 IU/kg SC 2 times/wk. Maintenance: 25 & 50 IU/kg 2 times/wk.
Ped hemodialysis patient 50 IU/kg IV 3 times/wk. Maintenance:
>30 kg 30-100 IU/kg 3 times/wk,
10-30 kg 60-150 IU/kg 3 times/wk,
<10 kg 74-150 IU/kg 3 times/wk.
Cancer patient 150 IU/kg SC 3 times/wk.
HIV-infected patient on zidovudine 100 IU/kg IV/SC 3 times/wk for 8 wk.
Adult surgery patient in an autologous predonation program 600 IU/kg IV 2 times/wk for 3 wk prior to surgery.
Perisurgery patient w/o autologous blood donation 600 IU/kg daily for 10 days before surgery & repeat on day of surgery, then continue for 4 days after surgery.
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